Living cells constantly rearrange themselves to adapt to changing environments and to perform their essential functions. The genome, membranous networks, and cell shape are all modified by molecular machines that exert mechanical forces. Some of these forces are produced by the ends of microtubules – dynamic cytoskeletal polymers that can push and pull on various objects. In our lab, we study these processes by reconstituting them using purified components “from the bottom up”, and performing quantitative microscopy.
biochemistry
in vitro reconstitution
microscopy
data analysis
News
- Wellcome Trust CDAThe lab has received news that we will be funded by a Wellcome Trust Career… Read more: Wellcome Trust CDA
- How do microtubules grow?New preprint! In collaboration with the lab of Maxim Igaev from the University of Dundee… Read more: How do microtubules grow?
- Welcome Lauren!Lauren Stokes has recently joined the lab after having graduated with a 1st class MBio… Read more: Welcome Lauren!